Characteristics of study participants and association with M genitalium cervical and/or endometrial infection
| Characteristic | M. genitalium positive | M. genitalium negative | OR (95% CI) | AOR (95% CI) |
| N = 88 | N = 498 | |||
| n (%)* | n (%)† | |||
| Demographics | ||||
| Age | ||||
| <25 years | 71 (18.2) | 319 (81.8) | 2.3 (1.3 to 4.1) | 2.7 (1.5 to 4.7) |
| ≥25 years | 17 (8.7) | 179 (91.3) | ||
| Race/ethnicity | ||||
| African-American | 69 (16.2) | 358 (83.8) | 1.4 (0.8 to 2.4) | –‡ |
| White/Hispanic/other | 19 (11.9) | 140 (99.1) | ||
| Marital status | ||||
| Unmarried | 71 (14.7) | 411 (85.3) | 1.4 (0.6 to 3.1) | –‡ |
| Married | 7 (11.3) | 55 (88.7) | ||
| Education | ||||
| <High school | 38 (16.7) | 189 (83.3) | 1.2 (0.8 to 2.0) | –‡ |
| ≥High school | 50 (13.9) | 308 (86.0) | ||
| Sexual health | ||||
| Sexually active | ||||
| Yes | 78 (15.8) | 415 (84.2) | 1.6 (0.8 to 3.1) | –‡ |
| No | 10 (10.7) | 83 (89.2) | ||
| Two or more life time sexual partners | ||||
| Yes | 10 (17.9) | 46 (82.1) | 1.3 (0.6 to 2.6) | –‡ |
| No | 78 (14.7) | 452 (85.3) | ||
| New sexual partner in past month | ||||
| Yes | 10 (17.5) | 47 (82.5) | 1.2 (0.6 to 2.5) | –‡ |
| No | 78 (14.7) | 451 (85.3) | ||
| History of STI§ | ||||
| Yes | 52 (15.0) | 295 (85.0) | 1.0 (0.6 to 1.6) | –‡ |
| No | 35 (15.0) | 198 (85.0) | ||
| History of bacterial vaginosis | ||||
| Yes | 13 (10.0) | 117 (90.0) | 0.6 (0.3 to 1.0) | –‡ |
| No | 73 (16.7) | 365 (83.3) | ||
| History of PID | ||||
| Yes | 23 (12.9) | 155 (87.1) | 0.8 (0.5 to 1.3) | –‡ |
| No | 64 (15.9) | 338 (84.1) | ||
| Hormonal contraception use | ||||
| Yes | 17 (15.6) | 92 (84.4) | 0.9 (0.5 to 1.8) | –‡ |
| No | 61 (15.9) | 323 (84.1) | ||
| Rare/occasional condom use¶ | ||||
| Yes | 60 (17.2) | 289 (82.8) | 1.4 (0.8 to 2.6) | –‡ |
| No | 18 (12.5) | 126 (87.5) | ||
| Consistent condom use** | ||||
| Yes | 7 (10.9) | 57 (89.1) | 1.2 (0.5 to 2.7) | –‡ |
| No | 71 (16.5) | 358 (83.5) | ||
| Oral sex | ||||
| Yes | 23 (17.6) | 108 (82.4) | 1.2 (0.7 to 2.0) | –‡ |
| No | 63 (15.0) | 356 (85.0) | ||
| Anal sex | ||||
| Yes | 4 (21.1) | 15 (78.9) | 1.5 (0.5 to 4.7) | –‡ |
| No | 84 (14.8) | 483 (85.2) | ||
| Age at sexual debut | ||||
| ≤15 years | 48 (15.8) | 255 (84.2) | 1.1 (0.7 to 1.8) | –‡ |
| >15 years | 40 (14.1) | 243 (85.9) | ||
| Behavioural | ||||
| Vaginal douche two or more times in past month | ||||
| Yes | 26 (22.8) | 88 (77.8) | 1.9 (1.2 to 3.3) | 2.0 (1.2 to 3.4) |
| No | 62 (13.1) | 410 (86.9) | ||
| Illicit drug use | ||||
| Yes | 32 (20.4) | 125 (79.6) | 1.7 (1.0 to 2.7) | –‡ |
| No | 56 (13.1) | 370 (86.9) | ||
| Current smoker | ||||
| Yes | 49 (20.2) | 194 (79.8) | 1.9 (1.2 to 3.1) | 2.0 (1.3 to 3.3) |
| No | 39 (11.5) | 301 (88.5) | ||
| Alcohol use | ||||
| Yes | 48 (14.8) | 277 (85.2) | 0.9 (0.6 to 1.5) | –‡ |
| No | 40 (15.5) | 218 (84.5) | ||
| Alcohol drinks per week | ||||
| >7 drinks | 13 (19.1) | 55 (80.9) | 1.4 (0.7 to 2.7) | –‡ |
| ≤7 drinks | 75 (14.6) | 440 (85.4) |
Missing observations: marital status, n = 42; education, n = 1; history of sexually transmitted infection (STI), n = 6; history of bacterial vaginosis, n = 18; history of pelvic inflammatory disease (PID), n = 6; hormonal contraception use, n = 93; condom use, n = 93; oral sex, n = 36; drug use, n = 3; smoking, n = 3, alcohol use, n = 3.
↵* Percentage of total study population with characteristic that tested positive for M genitalium.
↵† Percentage of total study population with characteristic that tested negative for M genitalium.
↵‡ Variables with a p value greater than 0.10 were not included in the multivariate analysis.
↵§ History of N gonorrhoeae, C trachomatis, or Trichonomas vaginalis.
↵¶ Condoms used 0 to 5 out of 10 sexual encounters.
↵** Condoms used 10 out of 10 sexual encounters. AOR, adjusted odds ratio; OR, odds ratio.