Table 2

List of enzymes involved in glycan metabolism derived from bacterial lateral gene transfers (LGTs)*

EC number†Enzyme nameRefSeq accessionNearest neighbour in phylogeny
3.2.1.18Exo-α-sialidaseXP_001319692Bacteroidetes
3.2.1.23β-galactosidaseXP_001581038Bacteroidetes
3.2.1.52β-N-acetylhexosaminidaseXP_001329989Bacteroidetes
3.2.1.24α-mannosidaseXP_001579222Prokaryotes
3.2.1.25β-mannosidaseXP_001322689Proteobacteria
3.2.1.51α-fucosidaseXP_001316088Bacteria
4.1.3.3N-acetylneuraminate lyaseXP_001323296Pasteurellaceae (γ-proteobacteria)
5.1.3.8Acylglucosamine 2-epimeraseXP_001308218Bacteroidetes
3.2.1.45GlucosylceramidaseXP_001279673Bacteroidetes
  • *For details about inference of LGT methodology and gene and enzyme characteristics see ref. 26. Note that some of the listed enzymes could target O-glycans, N-glycans and/or gangliosides.

  • †EC, Enzyme commission number.