Alcohol intake by human papillomavirus (HPV) infection status and HPV prevalence by quartiles of alcohol intake
| Median grams of alcohol intake per day by HPV infection status | HPV prevalence by quartiles* of grams of alcohol intake per day | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| No. | Median | (IQR) | p Value† | Q1 N (%) | Q2 N (%) | Q3 N (%) | Q4 N (%) | p Value‡ | |
| HPV negative | 514 | 3.13 | (0.1– 9.9) | 129 (43.3) | 128 (43.8) | 128 (42.1) | 129 (31.1) | ||
| Positive for: | |||||||||
| Any HPV | 795 | 4.52 | (0.6 –15.5) | <0.001 | 169 (56.7) | 164 (56.2) | 176 (57.9) | 286 (68.9) | <0.001 |
| Oncogenic HPV | 368 | 5.23 | (1.1 –18.3) | <0.001 | 68 (22.8) | 72 (24.7) | 82 (27.0) | 146 (35.2) | <0.001 |
| Non-oncogenic HPV | 211 | 5.29 | (0.6–17.5) | 0.006 | 48 (16.1) | 35 (12.0) | 47 (15.5) | 81 (19.5) | 0.002 |
| HPV 6, 11, 16 or 18§ | 197 | 6.31 | (1.2 –19.4) | <0.001 | 35 (11.7) | 35 (12.0) | 46 (15.1) | 81 (19.5) | <0.001 |
Bold font indicates a statistically significant p value.
*Alcohol intake was categorised by the quartile intake values among HPV-negative men.
†p Values were calculated using the Wilcoxon rank-sum test comparing the median value of alcohol consumption by HPV negativity versus HPV positivity.
‡p Values were calculated by the χ2 test for the distribution of HPV positivity compared with HPV negativity by quartiles of alcohol intake. The percentages presented are prevalence using the total number of subjects within each quartile of intake as the denominator.
§HPV 6, 11, 16 or 18 are the quadrivalent vaccine HPV types.
Qn, quartile.