Clinic attendance, demographic information and history of sexually transmitted infections for rectal LGV cases compared with symptomatic controls
| Characteristic | Cases N (%) | Controls N (%) | OR (95% CI) | p Value |
|---|---|---|---|---|
| N=98 | N=81 | |||
| Recruitment setting | ||||
| HIV clinic | 65 (66) | 55 (68) | Ref | 0.757* |
| Genitourinary medicine clinic | 27 (28) | 23 (28) | 0.99 (0.51 to 1.93) | |
| Other† | 6 (6) | 3 (4) | 1.69 (0.40 to 7.08) | |
| Reason attended clinic | ||||
| Symptoms | 75 (78) | 72 (89) | Ref | 0.075* |
| Routine/check up | 12 (12) | 3 (4) | 3.84 (1.04 to 14.17) | |
| Other‡ | 9 (9) | 6 (7) | 1.44 (0.49 to 4.25) | |
| Age median (IQR) | 39.5 (34–46) | 37 (30–44) | n/a | 0.087§ |
| Ethnicity—white (UK or other) | 87 (90) | 63 (79) | 2.35 (1.01 to 5.47) | 0.048 |
| Born in UK | 54 (56) | 53 (65) | 0.66 (0.36 to 1.22) | 0.186 |
| Known HIV-positive | 88 (90) | 58 (72) | 3.49 (1.55 to 7.87) | 0.003 |
| Previous hepatitis C | 10 (10) | 8 (10) | 1.02 (0.38 to 2.73) | 0.964 |
| Previous gonorrhoea | 67 (68) | 43 (54) | 1.86 (1.01 to 3.43) | 0.047 |
| Previous syphilis | 47 (48) | 31 (39) | 1.46 (0.80 to 2.65 | 0.219 |
| Previous LGV | 16 (16) | 8 (10) | 1.76 (0.71 to 4.34) | 0.223 |
| Previous chlamydia (non-LGV) | 51 (52) | 30 (38) | 1.81 (0.99 to 3.30) | 0.054 |
| Any previous sexually transmitted infection | 97 (99) | 67 (84) | 18.82 (2.4 to 147.3) | 0.005 |
HIV postexposure prophylaxis related: one case and two controls. Serological tests for syphilis follow-up: one case. Confirm new HIV: one control.
*p Value for trend.
†MSM or SW dedicated clinics.
‡Contact tracing: six cases and three controls.
§Wilcoxon rank sum test for medians.
LGV, lymphogranuloma venereum; MSM, men who have sex with men; SW, sex worker.