Univariate and multivariable analyses of patient characteristics associated with Neisseria gonorrhoeae with a ceftriaxone MIC ≥0.015 mg/L among MSM, 2007–2013
| Patient characteristic | Ceftriaxone MIC ≥0.015 mg/L (%) | Crude OR (95% CI) | Adjusted OR (95% CI) |
|---|---|---|---|
| Age, years | |||
| <25 (n=928) | 273 (29.4) | 1 | |
| 25–34 (n=1853) | 573 (30.9) | 1.07 (0.90 to 1.28) | |
| 35+ (n=1422) | 433 (30.4) | 1.05 (0.88 to 1.25) | |
| Ethnicity | |||
| White (n=3386) | 1022 (30.2) | 1 | |
| Black Caribbean (n=124) | 39 (31.4) | 1.06 (0.72 to 1.56) | |
| Black African (n=75) | 17 (22.7) | 0.68 (0.39 to 1.17) | |
| Black other (n=62) | 18 (29.0) | 0.95 (0.54 to 1.64) | |
| Asian, including Chinese (n=221) | 84 (38.0) | 1.42 (1.07 to 1.88)* | |
| Other ethnicity (n=66) | 14 (21.2) | 0.62 (0.34 to 1.13) | |
| Mixed ethnicity (n=143) | 43 (30.1) | 0.99 (0.69 to 1.43) | |
| Sexual partners in the 3 months prior to diagnosis | |||
| 0–1 (n=920) | 276 (30.0) | 1 | |
| 2–5 (n=1920) | 601 (31.3) | 1.06 (0.90 to 1.26) | |
| 6+ (n=655) | 204 (31.1) | 1.05 (0.85 to 1.31) | |
| Sex abroad in the 3 months prior to diagnosis | |||
| No (n=2729) | 832 (30.5) | 1 | |
| Yes (n=487) | 139 (28.5) | 0.91 (0.74 to 1.13) | |
| Symptoms present | |||
| No (n=1104) | 387 (35.0) | 1 | 1 |
| Yes (n=2434) | 709 (29.1) | 0.76 (0.65 to 0.89)* | 0.77 (0.66 to 0.90)* |
| Previous gonorrhoea infection | |||
| No (n=1927) | 531 (27.6) | 1 | |
| Yes (n=1706) | 575 (33.7) | 1.34 (1.16 to 1.54)* | |
| Concurrent STI infection | |||
| No (n=2284) | 724 (31.7) | 1 | |
| Yes (n=866) | 275 (31.8) | 1.00 (0.85 to 1.19) | |
| HIV status | |||
| Negative (n=2053) | 650 (31.7) | 1 | |
| Positive (n=1124) | 348 (31.0) | 0.97 (0.83 to 1.13) | |
| Year | |||
| 2007 (n=365) | 105 (28.8) | 1 | 1 |
| 2008 (n=346) | 61 (17.6) | 0.53 (0.37 to 0.76)* | 0.55 (0.38 to 0.80)* |
| 2009 (n=494) | 212 (42.9) | 1.86 (1.39 to 2.49)* | 1.88 (1.40 to 2.52)* |
| 2010 (n=543) | 241 (44.4) | 1.98 (1.48 to 2.63)* | 1.98 (1.48 to 2.64)* |
| 2011 (n=577) | 195 (33.8) | 1.26 (0.95 to 1.68) | 1.29 (0.96 to 1.73) |
| 2012 (n=788) | 183 (23.2) | 0.75 (0.57 to 0.99)* | 0.76 (0.57 to 1.02) |
| 2013 (n=1090) | 282 (25.9) | 0.86 (0.66 to 1.13) | 0.87 (0.64 to 1.16) |
| Isolation site | |||
| Genital (n=2153) | 623 (28.9) | 1 | |
| Rectal (n=1618) | 514 (31.7) | 1.14 (0.99 to 1.31) | |
| Throat (n=403) | 135 (33.5) | 1.22 (0.98 to 1.53) | |
| Other (n=29) | 7 (24.1) | 0.78 (0.33 to 1.84) | |
*p<0.05.
MIC, minimum inhibitory concentration; MSM, men who have sex with men.