Elsevier

Contraception

Volume 51, Issue 5, May 1995, Pages 293-297
Contraception

The impact of oral contraception on vulvovaginal candidiasis

https://doi.org/10.1016/0010-7824(95)00079-PGet rights and content

Abstract

To evaluate risk factors related to sociodemographic and clinical variables, oral contraception and sexual behavior of women with recurrent vulvovaginal candidiasis, we conducted a case-control study comparing 153 patients with recurrent vulvovaginal candidiasis with both asymptomatic women with negative vaginal cultures and patients with nonrecurrent symptomatic vulvovaginal candidiasis. In logistic regression analysis, patients with recurrent Candida vaginitis were more likely than negative controls to have used any contraceptive method in the year before evaluation, to have used antibiotics in the month preceding the visit, and to have a higher number of lifetime sex partners. Compared to patients with nonrecurrent Candida vaginitis, patients with recurrent infection were more likely to use oral contraception and to have a higher frequency of monthly intercourse. The proportion of recur rent disease attributable to the pill averages 11–12%. We conclude that oral contraceptives may influence the recurrence of symptomatic vulvovaginal candidiasis.

Reference (13)

  • SobelJD

    Pathophysiology of vulvovaginal candidiasis

    J Reprod Med

    (1989)
  • SpinilloA et al.

    Epidemiologic characteristics of women with idiopathic recurrent vulvovaginal candidiasis

    Obstet Gynecol

    (1993)
  • OddsFC

    Candidosis of the genitalia

  • RothmanKJ

    Modern epidemiology

    (1986)
  • TaylorJW

    Simple estimation of population attributable risk from case-control studies

    Am J Epidemiol

    (1977)
  • FoxmanB

    The epidemiology of vulvovaginal candidiasis: Risk factors

    Am J Public Health

    (1990)
There are more references available in the full text version of this article.

Cited by (80)

  • The occurrence of vulvovaginal Candida species and their antifungal susceptibility pattern in HIV seropositive women in Ahvaz, Southwest Iran

    2020, Clinical Epidemiology and Global Health
    Citation Excerpt :

    A high rate of VVC was reported in women in the age range of the 20–29 years in many studies,17,28 which was consistent with our findings (24.68 ± 8.99 years), probably due to drug usage and or contraceptives. Spinillo et al. reported a high rate of Candidiasis among married women between 30 and 45 years with frequent sexual activity, reproductive history, and taking contraceptives.29 Our findings showed that the rate of pregnancy is significantly more frequent among women with VVC.

  • Vulvovaginitis and Cervicitis

    2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases
  • FSRH Guideline (March 2023) Intrauterine contraception

    2023, BMJ Sexual and Reproductive Health
View all citing articles on Scopus
View full text