Original researchLeukorrhea and bacterial vaginosis as in-office predictors of cervical infection in high-risk women
Section snippets
Materials and methods
The study population consisted of consecutive new obstetric and gynecologic patients seen in two resident-staffed, inner-city clinics in Los Angeles between August 2000 and April 2001. All patients invited to participate consented to inclusion in this study. Two clinic sites were utilized: 1) the Los Angeles Free Obstetric Clinic in Hollywood, and 2) the Cedars-Sinai Medical Center outpatient Obstetrics and Gynecology Clinic in West Los Angeles. The study protocol was approved by the Medical
Results
Of the 194 women evaluated for the study, 118 (60.8%) were pregnant. An overview of patient characteristics identified for the entire study population and stratified by pregnancy status is shown in Table 1. The overall rate of cervical infection, the primary outcome measure for this study, was 11% (10/194); only one woman was infected with gonorrhea alone, and four women (2%) were co-infected with both chlamydia and gonorrhea. Table 1 demonstrates that, except for patient age, there were no
Discussion
We have demonstrated that the presence of leukorrhea, in the presence or absence of bacterial vaginosis on microscopic examination in an outpatient setting, is strongly associated with concomitant cervical infection with C trachomatisor N gonorrhoeae. Multivariate analysis revealed that the presence of leukorrhea in particular was a very strong predictor of cervical infection, particularly with chlamydia, in both nonpregnant (RR = 58.7) and pregnant (RR = 15.7) patients, after considering age,
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