Elsevier

Microbes and Infection

Volume 14, Issue 15, December 2012, Pages 1411-1427
Microbes and Infection

The effects of environmental factors on the virulence of Trichomonas vaginalis

https://doi.org/10.1016/j.micinf.2012.09.004Get rights and content
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Abstract

This review focused on potential regulatory mechanisms of Trichomonas vaginalis virulence properties, cytoadherence, cytotoxicity, phagocytosis, hemolysis, induction of apoptosis, and immune evasion in response to environmental factors of the human urogenital tract, iron, zinc, and polyamines. Understanding the multifactorial nature of trichomonal pathogenesis and its regulation may help to unravel the survival strategies of trichomonads and to implement prevention policies, opportune diagnosis, and alternative treatments for control of trichomoniasis.

Keywords

Trichomonas vaginalis
Virulence
Iron
Cell contact
Zinc
Polyamines

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