Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Possible demographic consequences of AIDS in developing countries

Abstract

Simple mathematical models of the transmission dynamics of HIV that incorporate demographic and epidemiological processes to assess the potential impact of AIDS on human population growth and structure in developing countries suggest that AIDS is capable of changing population growth rates from positive to negative values over timescales of a few decades. The disease is predicted to have little if any impact on the dependency ratio of a population, defined as the number of children below age 15 years and elderly people over 64 years, divided by the number of adults between 15 to 64 years.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. World Health Organization (WHO). Wkly Epidemiol. Rec. 62, 301 (1987).

  2. Piot, P. & Carael, M. Br. med. Bull. (in the press).

  3. Quinn, T. C. et al. Science 234, 955–965 (1986).

    Article  ADS  CAS  Google Scholar 

  4. Brun-Vezinet, F. et al. Science 234, 955–963 (1984).

    Google Scholar 

  5. Mann, J. M. et al. Lancet ii, 707–709 (1986).

    Article  Google Scholar 

  6. Wendler, I. et al. Br. med. J. 293, 782–785 (1986).

    Article  CAS  Google Scholar 

  7. Biggar, R. J. Lancet i, 79–82 (1986).

    Article  Google Scholar 

  8. Melbye, M. et al. Lancet ii, 1,114–1,115 (1986).

    Google Scholar 

  9. Piot, P. et al. J. infect. Dis. 155, 1,108–1,112 (1987).

    Article  CAS  Google Scholar 

  10. Mann, J. M. et al. Lancet ii, 654–656 (1986).

    Article  Google Scholar 

  11. Piot, P. et al. Science 239, 573–579 (1988).

    Article  ADS  CAS  Google Scholar 

  12. Coutinho, R. A. et al. Ned. Tijdschr. Geneesk 130, 508 (1986).

    CAS  Google Scholar 

  13. Melbye, M. et al. Ann. intern. Med. 104, 496–451 (YEAR?).

  14. Weber, J. N. et al. Lancet i, 1,179–1,181 (1986).

    Article  Google Scholar 

  15. Kanki, P. J. AIDS 1, 141–145 (1987).

    CAS  PubMed  Google Scholar 

  16. Quinn, T. C. et al J. Am. med. Assoc. 257, 2,617–2,621 (1987).

    Article  CAS  Google Scholar 

  17. May, R. M., Anderson, R. M. & Johnson, A. M. Science (submitted).

  18. Anderson, R. M. J. R. statist. Soc. A (in the press).

  19. May, R M. & Anderson, R. M. Nature 326, 137–142 (1987).

    Article  ADS  CAS  Google Scholar 

  20. Piot, P. & Mann, J. M. Annts Inst. Pasteur, Paris 138, 125–132 (1987).

    Article  Google Scholar 

  21. Mann, J. et al. New Engl. J. Med. 316, 345 (1987).

    CAS  PubMed  Google Scholar 

  22. Kreiss, J. et al. New Engl. J. Med. 314, 414–418 (1986).

    Article  CAS  Google Scholar 

  23. D'Costa, I. J. et al. Sex. transm. Dis. 12, 64–67 (1985).

    Article  CAS  Google Scholar 

  24. Medley, G. F. et al. Nature 328, 719–721 (1987).

    Article  ADS  CAS  Google Scholar 

  25. Mann, J. M. et al. J. Am. med. Assoc. 255, 3,255–3,259 (1986).

    Article  CAS  Google Scholar 

  26. Anderson, R. M. et al. IMA. J. math. med. Biol. 3, 229–263 (1986).

    Article  CAS  Google Scholar 

  27. Anderson, R. M. et al. Lancet i, 1,073–1,075 (1987).

    Article  Google Scholar 

  28. Anderson, R. M. & May, R. M. Nature 280, 361–367 (1979).

    Article  ADS  CAS  Google Scholar 

  29. May, R. M. & Anderson, R. M. Nature 280, 455–461 (1979).

    Article  ADS  CAS  Google Scholar 

  30. Anderson, R. M. in Theoretical Ecology: Principles and Applications (ed. May, R. M.) 318–355 (Blackwell, Oxford, 1981).

    Google Scholar 

  31. Anderson, R. M. Lect. Math. Life Sci. 12, 1–68 (1979).

    Google Scholar 

  32. May, R. M. & Anderson, R. M. Math. Biosci. 76, 1–16 (1985).

    Article  Google Scholar 

  33. McLean, A. R. & Anderson, R. M. Epidem. Infec. 100, 111–133 (1988).

    Article  CAS  Google Scholar 

  34. Anderson, R. M. & May, R. M. Phil. Trans. R. Soc. B 314, 533–570 (1986).

    Article  CAS  Google Scholar 

  35. Isham, V. J. R. statist. Soc. A (in the press).

  36. Hethcote, H. W. & Yorke, J. A. Lect. Notes Biomaths. 56, 1–105 (1984).

    Article  Google Scholar 

  37. May, R. M., Anderson, R. M. & McLean, R. M. Math. Biosci. (in the press); Lect. Notes Biomath. (in the press).

  38. Brodt, H. R. et al. Dt. med. Wschr. 111, 1,175–1,180 (1986).

    Article  CAS  Google Scholar 

  39. Kaplan, J. E. et al. J. Am. med. Assoc. 257, 335–339 (1987).

    Article  CAS  Google Scholar 

  40. Goedert, J. J. et al. Lancet ii, 711–715 (1984).

    Article  Google Scholar 

  41. Zolla-Pazner, S. et al. Proc. natn. Acad. Sci. U.S.A. 84, 5,404–5,408 (1987).

    Article  CAS  Google Scholar 

  42. Plummer, F. A. et al. Lancet i, 1,293–1,295 (1983).

    Article  Google Scholar 

  43. Saulsbury, F. T. et al. Pediat. infect. Dis. J. 6, 544–549 (1987).

    Article  CAS  Google Scholar 

  44. Borkowsky, W. et al. Lancet i, 1,168–1,171 (1987).

    Article  Google Scholar 

  45. Mok. J. Q. et al. Lancet i, 1,164–1,168 (1987).

    Article  Google Scholar 

  46. Cameron, D. W. et al. Abstr. 3rd int. Conf. AIDS (Washington DC, 1987).

    Google Scholar 

  47. Van De Pierre, P. et al. Lancet ii, 524–527 (1985).

    Article  Google Scholar 

  48. Piot, P. et al. J. infect. Dis. 155, 1,108–1,112 (1987).

    Article  CAS  Google Scholar 

  49. Mann, J. J. New Scient. 113, 40–43 (1987).

    Google Scholar 

  50. May, R. M. Ecology 67, 1,115–1,126 (1986).

    Article  Google Scholar 

  51. Dietz, K. & Hadeler, K. P. J. Math. Biol. 26, 1–25 (1988).

    Article  MathSciNet  CAS  Google Scholar 

  52. Klovdahl, A. S. Soc. Sci. Med. 21, 1,203–1,216 (1985).

    Article  CAS  Google Scholar 

  53. Brun-Vezinet et al. Science 226, 453–456 (1984).

    Article  ADS  CAS  Google Scholar 

  54. John Hopkins University, Population Reports 7 Series L No. 6, 10–14 (1987).

  55. Wilson Carswell, J. & Lloyd, G. AIDS 1, 192–193 (1987).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Anderson, R., May, R. & McLean, A. Possible demographic consequences of AIDS in developing countries. Nature 332, 228–234 (1988). https://doi.org/10.1038/332228a0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/332228a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing