Abstract
Nonspecific bacterial vaginosis, defined as the presence of clue cells, was treated in a randomized, double-blind study with (1) tinidazole 2 g as a single dose (82 patients), (2) tinidazole 2 g on 2 consecutive days (84 patients), and (3) with placebo (81 patients). The cure rates, both clue cells and Gardnerella vaginalis absent, were 51, 74 and 4%, respectively. A closer clinical and microbiological evaluation showed the 2-day regimen to be superior.
Publication types
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Clinical Trial
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Comparative Study
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Randomized Controlled Trial
MeSH terms
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Adult
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Clinical Trials as Topic
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Double-Blind Method
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Drug Administration Schedule
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Female
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Gardnerella vaginalis / drug effects
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Haemophilus Infections / drug therapy*
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Humans
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Nitroimidazoles / administration & dosage*
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Random Allocation
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Tinidazole / administration & dosage*
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Tinidazole / therapeutic use
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Vaginal Diseases / drug therapy*
Substances
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Nitroimidazoles
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Tinidazole