Background: In England, screening for genital chlamydial infection has begun; however,
screening frequency for women is not yet determined. Aim: To measure chlamydia incidence …

Rationale: Pulmonary arterial hypertension (PAH) is a life-shortening condition. The
European Society of Cardiology and European Respiratory Society and the REVEAL (North …

Objectives: To present national trends of the estimated number and proportion of late HIV
diagnoses and short-term mortality following diagnosis among men who have had sex with …

Background: Ticagrelor has superior efficacy to clopidogrel in the management of acute
coronary syndromes but has not been assessed in patients undergoing percutaneous …

Mitochondrial dysfunction is postulated to be central to amyotrophic lateral sclerosis (ALS)
pathophysiology. Evidence comes primarily from disease models and conclusive data to …

Objectives: To detect and quantify current risk factors for HIV seroconversion among gay
men seeking repeat tests at sexual health clinics. Design: Unmatched case control study …

Objective To assess clinical, electrophysiological and whole-body muscle MRI
measurements of progression in patients with motor neuron disease (MND), as tools for …

Background: The incidence of Alzheimer disease (AD) is increasing with the ageing
population. The development of low cost non-invasive diagnostic aids for AD is a research …

Background Clinical phenotypic heterogeneity represents a major barrier to trials in motor
neuron disease (MND) and objective surrogate outcome measures are required, especially …

Background Fatigue is a widely experienced, incapacitating symptom of MS. It hinders daily
functioning and has deleterious effects on quality of life. The UK MS Register is an online …