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To determine whether human X-linked neonatal diabetes mellitus, enteropathy and
endocrinopathy syndrome (IPEX; MIM 304930) is the genetic equivalent of the scurfy (sf) …

Sclerosteosis is an autosomal recessive sclerosing bone dysplasia characterized by
progressive skeletal overgrowth. The majority of affected individuals have been reported in …

The influenza pandemic of 1918–19 was responsible for about 50 million deaths worldwide.
Modern histopathological analysis of autopsy samples from human influenza cases from …

Proteomic and lipidomic profiling was performed over a time course of acute hepatitis C
virus (HCV) infection in cultured Huh-7.5 cells to gain new insights into the intracellular …

Chronic immune activation and progression to AIDS are observed after SIV infection in
macaques but not in natural host primate species. To better understand this dichotomy, we …

The mechanisms responsible for the virulence of the highly pathogenic avian influenza
(HPAI) and of the 1918 pandemic influenza virus in humans remain poorly understood. To …

Van Buchem disease is an autosomal recessive sclerosing bone dysplasia characterized by
skeletal hyperostosis, overgrowth of the mandible, and a liability to entrapment of the …

Studies of the host response to virus infection typically focus on protein-coding genes.
However, non-protein-coding RNAs (ncRNAs) are transcribed in mammalian cells, and the …

Systems biology offers considerable promise in uncovering novel pathways by which
viruses and other microbial pathogens interact with host signaling and expression networks …