[HTML][HTML] A recombinant vesicular stomatitis virus Ebola vaccine

JA Regules, JH Beigel, KM Paolino… - … England Journal of …, 2017 - Mass Medical Soc
Background The worst Ebola virus disease (EVD) outbreak in history has resulted in more
than 28,000 cases and 11,000 deaths. We present the final results of two phase 1 trials of an …

A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

MG Joyce, HAD King, I Elakhal-Naouar… - Science translational …, 2021 - science.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
stresses the continued need for next-generation vaccines that confer broad protection …

Hepatitis B virus coinfection negatively impacts HIV outcomes in HIV seroconverters

HM Chun, MP Roediger, KH Hullsiek… - Journal of Infectious …, 2012 - academic.oup.com
Abstract (See the editorial commentary by Peters and Marston, on pages 166–8.)
Background. Understanding the impact of hepatitis B virus (HBV) in human …

A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of …

SA Peel, P Bright, B Yount, J Handy… - American Journal of …, 1994 - cdr.lib.unc.edu
Stepwise selection for increased mefloquine resistance in a line of Plasmodium falciparum
in vitro resulted in increased resistance to halofantrine and quinine, increased sensitivity to …

[HTML][HTML] A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge

KMG Wuertz, EK Barkei, WH Chen, EJ Martinez… - npj Vaccines, 2021 - nature.com
The emergence of SARS-CoV-2 variants of concern (VOC) requires adequate coverage of
vaccine protection. We evaluated whether a SARS-CoV-2 spike ferritin nanoparticle vaccine …

Comprehensive analysis of unique cases with extraordinary control over HIV replication

D Mendoza, SA Johnson, BA Peterson… - Blood, The Journal …, 2012 - ashpublications.org
True long-term nonprogressors (LTNPs)/elite controllers (ECs) maintain durable control over
HIV replication without antiretroviral therapy. Herein we describe 4 unique persons who …

The ABC transporter genes of Plasmodium falciparum and drug resistance

SA Peel - Drug resistance updates, 2001 - Elsevier
The seminal observations that (a) chloroquine-resistant Plasmodium falciparum strains
accumulate less drug than more sensitive parasites, and (b) chloroquine resistance could be …

[HTML][HTML] DNA vaccine delivered by a needle-free injection device improves potency of priming for antibody and CD8+ T-cell responses after rAd5 boost in a …

BS Graham, ME Enama, MC Nason, IJ Gordon… - PloS one, 2013 - journals.plos.org
Background DNA vaccine immunogenicity has been limited by inefficient delivery. Needle-
free delivery of DNA using a CO2-powered Biojector® device was compared to delivery by …

Episodic evolution mediates interspecies transfer of a murine coronavirus

RS Baric, B Yount, L Hensley, SA Peel… - Journal of …, 1997 - Am Soc Microbiol
Molecular mechanisms permitting the establishment and dissemination of a virus within a
newly adopted host species are poorly understood. Mouse hepatitis virus (MHV) strains …

Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques

HAD King, MG Joyce, I Lakhal-Naouar… - Proceedings of the …, 2021 - National Acad Sciences
Emergence of novel variants of the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) underscores the need for next-generation vaccines able to elicit broad and durable …