User profiles for "author:Douglas Taylor"
Douglas TaylorUniversity of Virginia Verified email at virginia.edu Cited by 7766 |
Methods of isolating extracellular vesicles impact down-stream analyses of their cargoes
DD Taylor, S Shah - Methods, 2015 - Elsevier
Viable tumor cells actively release vesicles into the peripheral circulation and other biologic
fluids, which exhibit proteins and RNAs characteristic of that cell. Our group demonstrated …
fluids, which exhibit proteins and RNAs characteristic of that cell. Our group demonstrated …
Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments
DD Taylor, C Gercel-Taylor - Seminars in immunopathology, 2011 - Springer
Cancer cells, both in vivo and in vitro, have been demonstrated to release membranous
structures, defined as microvesicles or exosomes, consisting of an array of macromolecules …
structures, defined as microvesicles or exosomes, consisting of an array of macromolecules …
History, chance and adaptation during biological invasion: separating stochastic phenotypic evolution from response to selection
Introduced species often exhibit changes in genetic variation, population structure, selection
regime and phenotypic traits as they colonize and expand into new ranges. For these …
regime and phenotypic traits as they colonize and expand into new ranges. For these …
Retracted: microRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
DD Taylor, C Gercel-Taylor - 2008 - Elsevier
OBJECTIVES: Most ovarian cancer patients are diagnosed at an advanced stage (67%) and
prospects for significant improvement in survival reside in early diagnosis. While expression …
prospects for significant improvement in survival reside in early diagnosis. While expression …
Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
Q Abdool Karim, SS Abdool Karim, JA Frohlich… - science, 2010 - science.org
The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed
the effectiveness and safety of a 1% vaginal gel formulation of tenofovir, a nucleotide …
the effectiveness and safety of a 1% vaginal gel formulation of tenofovir, a nucleotide …
Exosomal microRNA: a diagnostic marker for lung cancer
G Rabinowits, C Gerçel-Taylor, JM Day, DD Taylor… - Clinical lung cancer, 2009 - Elsevier
Purpose To date, there is no screening test for lung cancer shown to affect overall mortality.
MicroRNAs (miRNAs) are a class of small noncoding RNA genes found to be abnormally …
MicroRNAs (miRNAs) are a class of small noncoding RNA genes found to be abnormally …
[HTML][HTML] Preexposure prophylaxis for HIV infection among African women
Background Preexposure prophylaxis with antiretroviral drugs has been effective in the
prevention of human immunodeficiency virus (HIV) infection in some trials but not in others …
prevention of human immunodeficiency virus (HIV) infection in some trials but not in others …
Defective angiogenesis in mice lacking endoglin
DY Li, LK Sorensen, BS Brooke, LD Urness, EC Davis… - Science, 1999 - science.org
Endoglin is a transforming growth factor–β (TGF-β) binding protein expressed on the surface
of endothelial cells. Loss-of-function mutations in the human endoglin gene ENG cause …
of endothelial cells. Loss-of-function mutations in the human endoglin gene ENG cause …
[HTML][HTML] Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …
[HTML][HTML] Micro-Raman spectroscopy detects individual neoplastic and normal hematopoietic cells
Current methods for identifying neoplastic cells and discerning them from their normal
counterparts are often nonspecific, slow, biologically perturbing, or a combination thereof …
counterparts are often nonspecific, slow, biologically perturbing, or a combination thereof …