[HTML][HTML] Horizontal antimicrobial resistance transfer drives epidemics of multiple Shigella species

KS Baker, TJ Dallman, N Field, T Childs… - Nature …, 2018 - nature.com
Horizontal gene transfer has played a role in developing the global public health crisis of
antimicrobial resistance (AMR). However, the dynamics of AMR transfer through bacterial …

[HTML][HTML] Genomic epidemiology of Shigella in the United Kingdom shows transmission of pathogen sublineages and determinants of antimicrobial resistance

KS Baker, TJ Dallman, N Field, T Childs, H Mitchell… - Scientific reports, 2018 - nature.com
Shigella are globally important diarrhoeal pathogens that are endemic in low-to-middle
income nations and also occur in high income nations, typically in travellers or community …

[HTML][HTML] Rapid increase in lymphogranuloma venereum in men who have sex with men, United Kingdom, 2003 to September 2015

T Childs, I Simms, S Alexander, K Eastick… - …, 2015 - eurosurveillance.org
United Kingdom (UK) national data show a sharp increase in diagnoses of
lymphogranuloma venereum (LGV) since 2012. Most cases are in men who have sex with …

What is the overlap between HIV and shigellosis epidemics in England: further evidence of MSM transmission?

K Mohan, M Hibbert, G Rooney, M Canvin… - Sexually transmitted …, 2018 - sti.bmj.com
Background Evidence suggests that sexual transmission between men has replaced foreign
travel as the predominant mode of Shigella transmission in England. However, sexuality and …

Prevalence and characteristics of gastrointestinal infections in men who have sex with men diagnosed with rectal chlamydia infection in the UK: an 'unlinked …

G Hughes, P Silalang, J Were, H Patel… - Sexually transmitted …, 2018 - sti.bmj.com
Introduction Gastrointestinal infections (GII) can cause serious ill health and morbidity.
Although primarily transmitted through faecal contamination of food or water, transmission …

Neurocognition and quality of life after reinitiating antiretroviral therapy in children randomized to planned treatment interruption

J Ananworanich, D Melvin, JTR Amador, T Childs… - Aids, 2016 - journals.lww.com
Objective: Understanding the effects of antiretroviral treatment (ART) interruption on
neurocognition and quality of life (QoL) are important for managing unplanned interruptions …

[HTML][HTML] Outcomes after viral load rebound on first-line antiretroviral treatment in children with HIV in the UK and Ireland: an observational cohort study

T Childs, D Shingadia, R Goodall, K Doerholt… - The Lancet …, 2015 - thelancet.com
Background About a third of children with HIV have virological failure within 2 years of
beginning antiretroviral treatment (ART). We assessed the probability of switch to second …

[HTML][HTML] Common determinants of antimicrobial resistance in sequential episodes of sexually transmitted shigellosis in men who have sex with men: a cross-sectional …

KS Baker, TJ Dallman, N Field, T Childs, J Were… - The Lancet, 2017 - thelancet.com
Background In high-income nations, men who have sex with men (MSM) are at increased
risk of shigellosis. A sublineage of Shigella flexneri serotype 3a was recently shown to have …

Factors associated with wide variation in clinical litigation rates across acute NHS trusts in England: a cross-sectional analysis

B Griggs, T Childs, J Birkinshaw… - International Journal for …, 2021 - academic.oup.com
Objective Identify organizational factors associated with high clinical litigation rates among
acute National Health Service (NHS) trusts in England. Design Cross-sectional analysis …

Safety of zidovudine/lamivudine scored tablets in children with HIV infection in Europe and Thailand

H Bailey, L Thompson, T Childs, I Jeannie… - EUROPEAN JOURNAL …, 2016 - flore.unifi.it
BACKGROUND: Zidovudine (ZDV) has been associated with risk of haematological toxicity.
Safety data from clinical trials is generally limited to 48 weeks. We assessed the short-and …