You are here

Article Text

Article menu
Download PDFPDF
Case report
Unusual muscle disease in HIV infected patients
  1. S Roedling1,
  2. D Pearl1,
  3. H Manji2,
  4. M G Hanna2,
  5. J L Holton3,
  6. R F Miller1,4
  1. 1Patrick Manson Unit, University College London Hospitals, London WC1E 6AU, UK
  2. 2Centre for Neuromuscular Disease, Department of Molecular Neuroscience, Institute of Neurology, University College London and National Hospital for Neurology and Neurosurgery, London WC1N 3BG, UK
  3. 3Department of Molecular Neuroscience and Division of Neuropathology, Institute of Neurology, University College London and National Hospital for Neurology and Neurosurgery, London WC1N 3BG, UK
  4. 4Centre for Sexual Health and HIV Research, Department of Primary Care and Population Sciences, Royal Free and University College Medical School, University College London, and Camden Primary Care Trust, Mortimer Market Centre, London WC1E 6AU, UK
  1. Correspondence to:
 Dr Rob Miller
 Centre for Sexual Health and HIV Research, Department of Primary Care and Population Sciences, Royal Free and University College Medical School, University College London, and Camden Primary Care Trust, Mortimer Market Centre, London WC1E 6AU, UK; rmillergum.ucl.ac.uk.uk

Abstract

Two patients presented with proximal muscle weakness, a normal or minor elevation of creatine phosphokinase (CPK) and normal findings on electromyography. Muscle biopsy in one patient revealed CD8+ polymyositis, and in the other showed ddI induced myopathy. These cases illustrate the importance of muscle biopsy in identifying the underlying pathology in HIV infected patients with muscle weakness and little or no abnormality in laboratory investigations.

  • CPK, creatine phosphokinase
  • EMG, electromyography
  • ESR, erythrocyte sedimentation rate
  • FBC, full blood count
  • NRTI, nucleoside reverse transcriptase inhibitors
  • HIV
  • muscle weakness

https://doi.org/10.1136/sti.2003.008474

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    View Full Text

    Footnotes

    Linked Articles

    • Brief Encounters
      Brief Encounters
      Rob Miller Helen Ward
      Sexually Transmitted Infections 2004; 80 251-251 Published Online First: 04 Aug 2004.