Footnotes

• Handling editor Anna Maria Geretti

• Contributors SN performed medical visits and contributed to the writing of the article. ARR contributed to the writing of the article and collected clinical data. EB and AC contributed to the review of the article. MC performed medical visits. LG collected and analysed clinical data and contributed to the review of the article. FA contributed to the writing of the article. NM coordinated microbiological activities and contributed to the review of the article. All authors have read and agreed to the published version of the manuscript.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests None declared.

• Provenance and peer review Not commissioned; internally peer reviewed.

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