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Three day oral course of Augmentin to treat chancroid.
  1. J O Ndinya-Achola,
  2. H Nsanze,
  3. P Karasira,
  4. L Fransen,
  5. L J D'Costa,
  6. P Piot,
  7. A R Ronald


    Amoxycillin and clavulanic acid (Augmentin; Beecham Research Laboratories) was used to treat patients with bacteriologically proved chancroid in three different dose regimens. A single dose of Augmentin (amoxycillin 3 g, clavulanic acid 350 mg) was found to be ineffective. A similar dose repeated after 24 hours was equally ineffective, but a dose (amoxycillin 500 mg, clavulanic acid 250 mg) given every 8 hours for three days was found to be effective. The drug was well tolerated and no side effects were noted in any of the patients treated.

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