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Editor,—There has been a progressive rise in the prevalence of human immunodeficiency virus (HIV) infection in India, which currently has the largest number of HIV infected people in the world.1 The spread of HIV is predominantly by heterosexual transmission in India.2 Sexually transmitted disease (STD), particularly genital ulcer disease (herpes, syphilis, and chancroid), has an important role in the transmission of HIV, and the two have been observed to be interrelated.3, 4 We conducted a pilot study to assess the relation between syphilis and HIV infection among non-pregnant women attending gynaecology and STD clinics of our hospital. …