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Screening of asymptomatic Chlamydia trachomatis (CT) infections is indicated to prevent the spread of CT and the development of secondary complications like pelvic inflammatory disease, ectopic pregnancy, and tubal infertility. Cost effectiveness presents an important aspect in the decision making regarding actual implementation. A recent paper in this journal by Van Valkengoed et al1 addressed cost effectiveness, using an established pharmacoeconomic model,2 of a systematic screening programme for asymptomatic CT infections in women registered in general practices in Amsterdam, based on mailed home obtained urine specimens.3 The aim of this letter is to extend the application of the pharmacoeconomic model with regard to pooling and improved …