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Immune reconstitution eosinophilia due to schistosomiasis
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A 21 year old black African heterosexual woman, formerly resident in south east Africa, presented in early October 2000 on arrival in the United Kingdom. Examination revealed hepatosplenomegaly. Investigation showed Hb = 10.2 g/dl, WBC = 2.9 × 109/l (neutrophils = 1.5, lymphocytes = 0.8, and eosinophils = 0.3 × 109/l). Blood urea and electrolytes were normal. Liver function tests showed alkaline phosphatase = 1704 (normal = 45–122) U/l, and alanine transaminase = 65 (normal = 7–63) U/l. Hepatitis A and C serology was negative; hepatitis B serology showed sAg negative …