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The patient was a 36 year old white man with recently diagnosed AIDS. At HIV diagnosis, his HIV viral load was > 500 000 copies/ml and his CD4 cells were 40 cells ×106/l. Six weeks after his AIDS diagnosis, he presented with fevers, night sweats, chills, and dysuria. An Escherichia coli urinary tract infection was diagnosed and he was treated with levofloxacin for 14 days. Symptoms continued, he was found to have E coli bacteraemia, and he was referred for inpatient evaluation.
He was exclusively heterosexual, denied injecting drug use, and had over 400 sexual partners in the past year. He travelled extensively in the United States, and had lived in Key West, Florida, and Los Angeles.
On admission to hospital, he was afebrile, had bilateral temporal wasting, and leucoplakia but no adenopathy. The respiratory, cardiovascular, abdominal, and central nervous systems were …