Article Text

Download PDFPDF
Vulvovaginal carriage of yeasts other than Candida albicans
  1. J Holland1,
  2. M L Young1,
  3. O Lee2,
  4. S C-A Chen2
  1. 1Mayne Health-Laverty Pathology, NSW, Australia
  2. 2ICPMR, Westmead Hospital, NSW, Australia
  1. Correspondence to:
 Dr Juliette Holland, Mayne Health-Laverty Pathology, 60 Waterloo Road, North Ryde, NSW 2113, Australia; 


Aims: We investigated the spectrum of yeasts isolated, and compared the epidemiological and laboratory characteristics of women carrying vulvovaginal Candida albicans with those carrying yeasts other than C albicans.

Method: Between April and June 2001, 5802 consecutively received genital swabs from women were plated onto Candida ID chromogenic media (BioMerieux). Blue colonies were reported as C albicans; all other colonies (white and pink) were identified to species level using the Vitek YBC card (BioMerieux). In vitro susceptibility to amphotericin (AMB), fluconazole (FLU), itraconazole (ITZ), and voriconazole (VOR) was determined for approximately 40% of non-C albicans yeasts using a standardised microdilution method.

Results: Yeast was isolated from 1221 women (21%). Of these, C albicans only was isolated from 1087 (89%) and yeasts other than C albicans from 129 (11%) women. C glabrata comprised 89 (69%) of the latter. Women in whom other yeasts were recovered were older than those with C albicans (mean 43, versus 33 years, p <0.001). All isolates tested (n=53) were susceptible to AMB and VOR. Seven (24%) C glabrata strains were susceptible to FLU with 21 (72%) testing susceptible-dose dependent.

Conclusion: Yeasts other than C albicans are common vaginal isolates even in a primary care population. The species isolated are less susceptible to FLU than most C albicans.

  • vulvovaginal yeasts
  • Candida glabrata
  • Candida albicans

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.