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Letters
Clearance of HPV infection in middle aged men and women after 9 years’ follow up
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The age prevalence of human papillomavirus (HPV) cervical infections is high in young age groups, declining sharply thereafter, reaching a steady state after age 40.1 Women who remain persistent carriers of HPV DNA are considered at high risk for cervical cancer. To investigate viral persistence over an extended period of time, we re-contacted, in 1997–8, a group of women who participated in case-control studies between 1988–91 in Spain, Colombia, and Brazil.2–,4 Among women with confirmed normal cervical smears, follow up was scheduled for all women positive …