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Lower motor neuron syndrome and HIV infection
  1. D Pearl,
  2. M Noursadeghi,
  3. H Manji,
  4. S Edwards,
  5. R Miller
  1. Patrick Manson Unit, University College London Hospitals, London and Department of Sexually Transmitted Diseases, RFUCMS, University College London, London WC1E 6AU, UK.
  1. Correspondence to:
    Rob Miller, Department of Sexually Transmitted Diseases, RFUCMS, University College London, London WC1E 6AU, UK;
    rmiller{at}gum.ucl.ac.uk

https://doi.org/10.1136/sti.79.4.351

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    A 33 year old right handed male injection drug user presented with a 4 week history of progressive shoulder and upper arm weakness and difficulty in speaking, together with a 2 week history of fever and a productive cough. He had been HIV-1 antibody positive for 16 years, had no AIDS defining illness, and was on no antiretroviral therapy. The CD4 count was 110 cells ×106/l and viral load was 56 000 copies/ml. There was no past history of, nor had the patient recently been vaccinated against, poliomyelitis; the patient was HB anticore and hepatitis C antibody positive. There was no family history of neurological disease.

    On examination there were signs of …

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