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Collecting the essence of man: semen collection for HIV transmission studies in sub-Saharan Africa
  1. M A Price1,2,
  2. M S Cohen1,2,
  3. I F Hoffman2,
  4. D Chilongozi3,
  5. F E A Martinson3,
  6. T Tembo3
  1. 1Department of Epidemiology, University of North Carolina at Chapel Hill, NC, USA
  2. 2School of Medicine, University of North Carolina at Chapel Hill, NC, USA
  3. 3UNC Project, Lilongwe, Malawi
  1. Correspondence to:
 Matt Price
 International AIDS Vaccine Initiative, 901 Mariners Island Blvd, Suite 555, San Mateo, CA 94404, USA; mpriceiavi.org

https://doi.org/10.1136/sti.2004.012104

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    Efforts to understand male to female sexual transmission of HIV must include semen analysis. Estimating sexual infectiousness using blood HIV RNA concentrations as a surrogate marker may be biased.1 Semen is routinely collected in Europe and the United States for HIV research2 and has recently been collected in clinical trials in sub-Saharan Africa3; however, there are no published data about issues associated with semen collection.

    We conducted a study at the Central Hospital in Lilongwe, Malawi, from January 2000 to June 2001 to better understand the relation between trichomonas and HIV-1 viral load.4 Men attending STI and dermatology clinics consented and were enrolled. All men with Trichomonas vaginalis and a comparison group of …

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    Footnotes

    • This study has been approved by the UNC Chapel Hill School of Medicine ethics board (Chapel Hill, NC, USA), and the Malawi Health Sciences Research Committee (Lilongwe, Malawi).

    • No authors have competing interests and all have contributed to the creation of this manuscript.