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Alcohol and drug use in the context of anal sex and other factors associated with sexually transmitted infections: results from a multi-city study of high-risk men who have sex with men in the USA
  1. G Mansergh1,
  2. S Flores1,
  3. B Koblin2,
  4. S Hudson3,
  5. D McKirnan4,
  6. G N Colfax5,
  7. the Project MIX Study Group
  1. 1
    CDC Division of HIV/AIDS Prevention, Atlanta, USA
  2. 2
    New York Blood Center, New York City, New York, USA
  3. 3
    Health Research Association, Los Angeles, USA
  4. 4
    University of Illinois-Chicago and Howard Brown Health Center, Chicago, USA
  5. 5
    San Francisco Department of Public Health, San Francisco, USA
  1. Gordon Mansergh, CDC Divison of HIV/AIDS Prevention, 1600 Clifton Rd, Mailstop E37, Atlanta 30333, USA; gcm2{at}


Men who have sex with men (MSM) who use alcohol and drugs are at especially high risk for sexually transmitted infections (STIs); more information is needed about associated factors to improve risk reduction. We assessed reported STIs and demographic and event-level alcohol and drug use characteristics associated with STIs in a diverse, multi-city study in the USA of MSM who use substances.

Improved risk reduction efforts are needed for this group as well as some initiatives tailored to men who are HIV positive, younger and use drugs (not alcohol) in the context of anal sex.

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  • Funding: This study was funded by a CDC cooperative agreement.

  • Competing interests: None.

  • Ethics approval: The protocol was reviewed and approved by the CDC Institutional Review Board and by local ethics review boards at each of the study sites.

  • The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the CDC.