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Low seroprevalence of syphilis in Burkina Faso
  1. Fati Kirakoya-Samadoulougou1,2,
  2. Marie-Christine Defer2,
  3. Seydou Yaro2,
  4. Paulin Fao2,
  5. François Ilboudo3,
  6. Youssouf Langani3,
  7. Nicolas Meda2,4,
  8. Annie Robert1,
  9. Nicolas Nagot5
  1. 1Pôle Epidémiologie et Biostatistique, Institut de Recherche Expérimentale et Clinique (IREC), Faculté de Santé Publique, Université Catholique de Louvain, Bruxelles, Belgium
  2. 2Centre Muraz, Bobo-Dioulasso, Burkina Faso
  3. 3Institut National de la Statistique et de la Démographie, Ouagadougou, Burkina Faso
  4. 4Département de Santé Publique, Université de Ouagadougou, Ouagadougou, Burkina Faso
  5. 5EA 4205 ‘Transmission, Pathogenèse et Prévention de l'Infection par le VIH’, Université Montpellier 1 and Department of Medical Information, CHU Montpellier, France
  1. Correspondence to Dr Fati Kirakoya-Samadoulougou, EPID, Clos, Chapelle-aux-Champs, 30, Boîte 30.58, Bruxelles 1200, Belgique; fati.kirakoya{at}


Background Little information is available on the epidemiology of syphilis in West Africa, where this infection is routinely screened in antenatal clinics to prevent congenital infection. In order to inform control programmes, the burden of active syphilis was estimated among pregnant women and adults in Burkina Faso.

Methods This study enrolled 2136 pregnant women from 98 healthcare facilities and 1679 consenting women and men from the general population of Ouagadougou, the capital city. After a face-to-face interview on demographic characteristics, blood samples were collected and tested for syphilis. Active syphilis was defined by a dually positive result on rapid plasma reagin and Treponema pallidum haemagglutination antibody tests.

Results The overall seroprevalence of active syphilis was 1.7% (95% CI 1.3 to 2.2), with similar rates between women (1.2%, 95% CI 0.7 to 2.3) and men (1.8%, 95% CI 1.0 to 3.0) in Ouagadougou, and a trend for higher prevalence among pregnant women from semi-urban areas (2.2%, 95% CI 1.0 to 4.5) compared with rural areas (1.7%, 95% CI 1.2 to 2.4, p=0.06). The prevalence tended to be higher among women aged 20–24 years (2.6%, 95% CI 1.3 to 7.6) and men aged 30–34 years (3.9%, 95% CI 0.8 to 11.0) than at other ages. However, age, marital status, location and education were not associated with syphilis.

Conclusion The low prevalence of syphilis among pregnant women and the adult general population is very encouraging but should not challenge the amount of resources dedicated to sexually transmitted infection and HIV prevention.

  • Burkina Faso
  • prevalence
  • rural
  • seroepidemiology
  • seroprevalence
  • syphilis
  • urban

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  • Part of the contents of this manuscript was presented at the 5th International AIDS Society conference on HIV pathogenesis, treatment and prevention, Cape Town (South Africa), 19–22 July 2009.

  • Funding This work was supported by the United Nations Development Programme (UNDP), WHO, the United Nations Population Fund (UNFPA), and the embassies of Holland, Switzerland, Denmark and Belgium.

  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval This study was conducted with the approval of the Ministry of Health of Burkina Faso.

  • Provenance and peer review Not commissioned; externally peer reviewed.