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We read the article of Zhou and collaborators1 with great interest. We agree that clinicians should be aware that appropriate therapy in early syphilis may be not sufficient for avoiding late-stage disease, neurosyphilis in particular. To support such an important issue, we would like to deliver the data we obtained by a retrospective study we conducted some years ago.
The data were collected in our Section of Dermatology by examining the clinical records of 62 patients diagnosed as having …
Competing interests None.
Ethics approval This is retrospective study in which subjects were regular patients with syphilis who have been treated with penicillin many years ago.
Provenance and peer review Not commissioned; internally peer reviewed.