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Predictors of serological cure and serofast state after treatment in HIV-negative patients with early syphilis in China
  1. Jun Li,
  2. Lin-Na Wang,
  3. He-Yi Zheng
  1. Department of Dermatology and Venereology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  1. Correspondence to Dr He-Yi Zheng, Department of Dermatology and Venereology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China; zhenghy62{at}hotmail.com

https://doi.org/10.1136/sextrans-2012-050711

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    Syphilis is a spirochetal infection with multiple manifestations. In recent years, syphilis has re-emerged as a significant public health problem in many countries including China.1 However, the factors that predict serological response after syphilis treatment have not been well-defined.

    We performed a retrospective study of patients who were diagnosed as having early syphilis in our clinic between the years 2000 and 2010. Analysis of factors determining the serological response to treatment was performed in HIV-negative patients with early syphilis, using demographic characteristics, clinical characteristics (i.e., sex, age, residence, coinfection with other STDs, …

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    Footnotes

    • Contributors H-YZ conceived, designed and coordinated the study; L-NW coordinated data collection; JL organised data for analysis; JL analysed the data, interpreted the results and wrote the manuscript.

    • Competing interests None.

    • Patient consent Obtained.

    • Ethics approval The study was approved by the ethics committee of Peking Union Medical College.

    • Provenance and peer review Not commissioned; internally peer reviewed.