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Universal perinatal screening for Treponema pallidum: the role of a dedicated infectious diseases team for prevention of mother-to-child transmission
  1. B Freyne1,
  2. A Stafford2,
  3. S Knowles3,
  4. A O Hora4,
  5. E J Molloy1,2,5,6
  1. 1 Department of Neonatology, National Maternity Hospital, Dublin, Ireland
  2. 2 Department of Paediatrics, University College Dublin School of Medicine and Medical Science, Ireland
  3. 3 Dept of Microbiology, National Maternity Hospital, Dublin, Ireland
  4. 4 Health Service Executive, Health Protection Surveillance Centre, Dublin, Ireland
  5. 5 Department of Paediatrics, Royal College of Surgeons in Ireland, Dublin, Ireland
  6. 6 Department of Neonatology, Our Lady's Hospital for Sick Children, Ireland
  1. Correspondence to Dr Bridget Freyne, Department of Neonatology, National Maternity Hospital, Holles Street, Dublin 2, Ireland; bridgetfreyne{at}

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Treponema pallidum is a significant perinatal pathogen with an estimated two million infections in pregnancy per annum.1 Universal antenatal screening is politically correct, safe and cost effective irrespective of national prevalence.2 Perinatal algorithms can be complex and require lengthy follow-up.3 Lost opportunities to prevent congenital syphilis are well described.4

We conducted a retrospective cross-sectional study of all seropositive pregnancies from two tertiary referral hospitals in Dublin, Ireland over a 5-year period (2005–2010). Data were analysed using SPSS V.14.0. Ethical approval was granted from both institutions. …

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  • Contributors BF: Study design, manuscript author, data analysis. AS: data analysis and collection. SK: Study design, data analysis. AO: Study design, data analysis. EJM: Study design, data analysis and supervising author.

  • Competing interests None.

  • Ethics approval National Maternity Hospital Ethics Committee and The Coombe Women's Hospital Ethics Committee.

  • Provenance and peer review Not commissioned; internally peer reviewed.