Background To evaluate the role of 5% KOH solution in the treatment of genital Molluscum contagiosum (MC) in adult female patients.

Methods All total 19 female patients with multiple genital MC were included for this study. All the patients were seronegative for the human immunodeficiency virus. Pregnant and lactating woman were not included in the study. It was a clinic based study. 5% KOH solution was applied to the skin lesions with swab stick. After 5 minutes skin lesions were washed with cold water gauge sponge. The procedure was repeated at 4 days interval. Patients were evaluated at the end of every 5 sittings and results were recorded.

Results 5 patients had complete clearance of their skin lesions by the end of 5 sittings. Another 11 patients had complete clearance of their skin lesions by the end of 10 sittings. Remaining patients had complete clearance of their skin lesions by the end of 15 sittings. Side effects of the treatment noted in the study were very few and very mild in nature

Conclusion This study showed that 5% KOH solution is a safe, inexpensive & effective clinic procedure for the treatment of genital MC in adult female patients. It is a simple technique with wide patient acceptance and with excellent cosmetic results. Side effects of the treatment noted in the study was very mild and well tolerated by the patients.