The treatment of infected cases, active case finding and the follow-up are the tasks of the dermato-venereological network. Since data on treated syphilis cases were available from decades back, a retrospective analysis was done.

Objective Syphilis patients treated between 1990–2011 in Szabolcs-Szatmár-Bereg county compared with national data, with the following criteria:

• Changes in morbidity in the county and in the country with sex distribution,

• Analysis by age group among women, especially during pregnancy,

• Distribution by diagnosis in women and in pregnant women including the trimester,

Results between 1990–2011, the outpatient clinic in Szabolcs-Szatmár-Bereg county treated a total of 469 syphilis cases (women n = 243/52%/, male n = 226/48%/),

• out of 243 patients, 69 had applied the syphilis diagnosis during pregnancy,

• The diagnosis of syphilis among pregnant women was as follows: primary syphilis 1/1.5%/, secondary syphilis: 17/25%/, early latent: 48/69.5%/, late latent: 3/4%/.

• between 1990–2000 the syphilis occurred sporadically among pregnant women, the number of however the cases between 2003–2008 increased significantly (in 1990–2000 n = 6; in 2001–2011 years n = 63),

• According the age group distribution, syphilis infection in pregnant women were most common in the 20–34 age-group(20–24/30%/, 25–29/20%%,30–34/23%/) and the 15–19 age group was also affected (16%)

• In terms of ethnicity, 49% of pregnant women (n = 34) was roma, 22% of them was from Ukraine, (n = 15) and 29% of them was Hungarian (n = 20),

Conclusions The following factors played a role in spreading of syphilis in Szabolcs-Szatmár-Bereg county

• The county’s geographic location.

• Significant illegal prostitution (cross-border, massage parlours, roadside, living prostitution),

• The lack of knowledge of the professions about syphilis

• Lack of knowledge of the population