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Raltegravir is a well-tolerated alternative third agent used in postexposure prophylaxis (PEP).1 ,2 In a single-centre study reviewing reasons for initiation and tolerability of raltegravir-PEP, we identified patients receiving PEP between February 2010 and April 2012. All patients receiving raltegravir-PEP were matched with standard-PEP controls (tenofovir-emtricitabine with lopinavir-ritonavir (LPV/r)). Ethical approval was not required as data was collected for service evaluation.
During this period 509 courses of PEP were prescribed, 33 (6.5%) containing raltegravir. Of the 61 cases analysed 66 (92%) were prescribed PEP following sexual exposure, 54/66 (82%) were male; 47/66 (71%) men who have sex with men. Of …
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