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Case report
Secondary syphilis presenting with aortitis and coronary ostial occlusion
  1. John A Chadwick1,
  2. Anita MacNab1,
  3. Jaydeep Sarma1,
  4. Simon Ray1,
  5. Isaac Kadir2,
  6. Eavan G Muldoon3,4
  1. 1Department of Cardiology, University Hospital of South Manchester, UK
  2. 2Department of Cardiothoracic Surgery, University Hospital of South Manchester, UK
  3. 3Department of Infectious Diseases, University Hospital of South Manchester, UK
  4. 4The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
  1. Correspondence to Dr Eavan G Muldoon, University Hospital of South Manchester, Southmoor Road, Manchester M23 9LT, UK; eavan.muldoon{at}


Aortitis is an established manifestation of tertiary syphilis. We report a rare case of aortitis with ostial occlusion and left ventricular failure in secondary syphilis. Her management required a true multidisciplinary approach from multiple specialities due to complications of concomitant psychosis and a history of anaphylaxis to penicillin. This case illustrates the complexities of diagnosing and managing a rare presentation of this increasingly prevalent infection.


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