Footnotes

• Competing interests ANP has received payments for presentations made at meetings sponsored by Gilead in spring 2015. NCN has received support for attendance at conferences, speaker fees and payments for attendance at advisory boards from Gilead Sciences, Viiv Healthcare, Janssen Pharmaceuticals and Bristol Myers Squibb and a research grant from Gilead Sciences. VC has received payment for lecturing by Merck Sharp & Dohmed Limited. DA has served on the advisory board for Gilead in January 2016.

• Patient consent Obtained.

• Ethics approval NRES committee London-Hampstead (approval number 13/LO/0246).

• Provenance and peer review Not commissioned; internally peer reviewed.

• Collaborators The AURAH study group: AdaR. Miltz, Alison J Rodger, Andrew Speakman, Fiona C Lampe, Andrew N Phillips, Janey Sewell, Lorraine Sherr, Richard J Gilson, David Asboe, Nneka C Nwokolo, Amanda Clarke, Mark M Gompels, Sris Allan, Simon Collins, Christopher Scott, Sara Day, Martin Fisher, Jane Anderson, Rebecca O’Connell, Monica Lascar, Vanessa Apea, Maneh Farazmand, Susan Mann, Jyoti Dhar, Daniel R. Ivens, Tariq Sadiq, Stephen Taylor, Michael Brady, Alan Tang, Rageshri Dhairyawan, Graham J Hart, Anne M Johnson, Alec Miners, and Jonathan Elford. AURAH clinic teams: Rageshri Dhairyawan, Sharmin Obeyesekera (Barking), Vanessa Apea, John Saunders, James Hand, Nyasha Makoka (Barts and the London), Stephen Taylor, Gerry Gilleran, Cathy Stretton (Birmingham), Martin Fisher, Amanda Clarke, Nicky Perry, Elaney Youssef, Celia Richardson, Louise Kerr, Mark Roche, David Stacey, Sarah Kirk (Brighton), Mark Gompels, Louise Jennings, Caroline Holder, Katie Anne Baker (Bristol), Maneh Farazmand, Matthew Robinson, Emma Street (Calderdale & Huddersfield), Sris Allan, Abayomi Shomoye (Coventry), Nneka Nwokolo, Ali Ogilvy (Dean Street), Jane Anderson, Sfiso Mguni, Rebecca Clark, Cynthia Sajani, Veronica Espa (Homerton), David Asboe, Sara Day, Ali Ogilvy, Sarah Ladd (John Hunter), Susan Mann, Michael Brady, Jonathan Syred, Lisa Hamza, Lucy Campbell, Emily Wandolo, Janagan Alagarajah (Kings), Linda Mashonganyika, Jyoti Dhar, Sally Batham (Leicester), Richard Gilson, Rita Trombin, Ana Milinkovic, Clare Oakland (Mortimer Market), Rebecca O’Connell, Nyasha Makoka (Newham), Alan Tang, Ruth Wilson, Elizabeth Green, Sheila O’Connor, Sarah Kempster, Katie Keating-Fedders (Reading), Daniel Ivens, Nicola Tyrrell, Jemima Rogers, Silvia Belmondo, Manjit Sohal (Royal Free), Tariq Sadiq, Wendy Majewska, Anne Patterson, Olanike Okolo, David Cox, Mariam Tarik,Charlotte Jackson, Jeanette Honigsbaum, Clare Boggon, Simone Ghosh, Bernard Kelly, Renee Aroney (St George’s), Christopher Scott, Ali Ogilvy (West London Clinic for Sexual Health), and Monica Lascar, Nyasha Makoka, Elias Phiri, Zandile Maseko (Whipps Cross).