Introduction Measure the incidence of syphilis among pregnant women overseen by Hospital de Clínicas from Universidade Federal do Triângulo Mineiro. Outline their epidemiological profile and assess their obstetrical assistance and immediate neonatal data.

Methods Retrospective study from survey of medical records from January 2007 to December 2015 of pregnant women diagnosed with syphilis, followed by the application of a structured questionnaire evaluating their epidemiological, obstetrical and neonatal data.

Results There were 226 cases of pregnant women with syphilis. This number grew from 9 cases (3.9%) in 2007 to 93 (41.2%) in 2015. Patients were, on average, 23.6 years old, ranging from 10 to 45 years. On obstetrical data, 74 (33.6%) were on their first pregnancy and the remaining had one or more pregnancies. 68.6% went to prenatal appointments and 69.4% were diagnosed on the second semester of their pregnancies. In 60.5% of the cases, the partner had not undertaken treatment. On births, 64.6% were vaginal births, 31.4% pre-term, 63.7% on term and 0.4% post-term births. On newborns, 68.6% weighed between 2,000–4000 grams; 72.1% had APGAR≥7% and 31% were diagnosed with congenital syphilis and hospitalised for further treatment.

Conclusion Congenital syphilis remains a challenge to public health mainly due to the alarming rise in new infections on recent years. It was present on women of all ages amid their reproductive period. Syphilis deserves attention because of its impact on mothers, partners and newborns.