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Handling editor Jackie A Cassell
Contributors WF and QZ were involved with the design of the study. WF and QZ were involved with patient recruitment. WF was responsible for single-pulse CO2 laser treatment and data collection. WF was responsible for laboratory testing and data collection. WF and QZ analysed the data and reviewed the manuscript.
Competing interests None declared.
Patient consent Obtained.
Ethics approval Ethics Committee of Changshu First People’s Hospital (No.csyy2010-1A).
Provenance and peer review Not commissioned; internally peer reviewed.
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