Footnotes

• Handling editor Jackie A Cassell

• Contributors AB and BJAR: study concept and design, acquisition of data, statistical analysis, analysis and interpretation of data, drafting of the manuscript, and finalising the article. KW and ML: acquisition of data, analysis and interpretation of data, critical revision of the manuscript for important intellectual content, and approval of the final article. HSMA: acquisition of data and approval of the final article. HMG: acquisition of data, critical revision of the manuscript for important intellectual content, and approval of the final article.

• Competing interests BJAR has received a research grant from Merck Sharp & Dohme (ongoing, 2014–2017) within the context of this article. Outside the context of this article he has received research grants from Gilead Sciences (ongoing, 2013–2017), has been an investigator of trials sponsored by Merck Sharp & Dohme, Gilead Sciences and Janssen-Cilag, has been an invited speaker for Gilead Sciences, Merck Sharp & Dohme, Pfizer and Janssen-Cilag, has participated on advisory boards and has received conference invitations for Bristol-Myers Squibb, AbbVie, Merck Sharp & Dohme, Gilead Sciences and Janssen-Cilag, and has been a consultant to GL Pharmaceuticals.

• Ethics approval DAHHS study: MEC-2015-643.

• Provenance and peer review Not commissioned; internally peer reviewed.

• Data sharing statement If additional data are needed by medical professionals or policymakers, the first author can be contacted at a.boerekamps@erasmusmc.nl.