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Archived vaginal samples are frequently used in ancillary research projects, yet few studies have validated their use for nucleic acid amplification analysis after long-term storage. This study sought to examine the suitability of vaginal swab samples for Chlamydia trachomatis transcription-mediated amplification analysis after up to 20 years of biobank storage.
Replication testing was conducted using a subset of vaginal swab samples originally obtained between May 1999 and June 2001 using …
Handling editor Anna Maria Geretti
Contributors All authors have seen and approved the manuscript, have contributed significantly to the work and do not have conflicts of interest to report.
Funding 1R56AI139189-01, National Institutes of Health.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; internally peer reviewed.