Article Text
Abstract
Background The infection by the human immunodeficiency virus (HIV), as well as the acquired immune deficiency syndrome (Aids), a worldwide epidemic, may lead to serious consequences in terms of maternal and fetal morbidity and mortality. The objective of this study was to describe the reproductive outcome and fetal growth in HIV-infected pregnant women and verify its relation to the antiretroviral use and severity of HIV infection.
Methods Cross-sectional study, with 122 pregnant women infected by HIV who had their termination in a university hospital maternity in Vitória, state of Espírito Santo, Brazil, from November 2001 to November 2014. The data was extracted from medical and public records in regard to gestational age, HIV status, antiretroviral use, and fetal dimensions.
Results Preterm birth occurred in 15.6% (19/122), low birth weight (LBW) in 22.1% (27/122) and small for gestational age fetal weight in 19.7% (24/122) of cases, without significant variation due to the HIV-status (only infected or Aids) or antiretroviral use.
Perinatal death occurred in 4.1% (5/122) of the cases. The Apgar score of less than or equal to 7 in the first minute was observed in 7.4% (9/120) and Zidovudine intravenous in prepartum was used in 92.5%(110/120) of cases. After a follow-up of more than 18 months of post¬natal life, vertical transmission (TV) was verified in 6 cases (4.9%; 6/122).
Conclusion LBW, small for gestational age fetal weight, preterm birth and perinatal death occurrences were higher than the expected values in this research, indicating the need for preventive actions.
Disclosure No significant relationships.