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P302 Achieving the third 90: keeping pregnant and breastfeeding women living with hiv virally suppressed in western nigeria
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  1. Saheed Usman1,
  2. Ibiwumi Usman2
  1. 1APIN Public Health Intiatives, Abuja, Nigeria
  2. 2Kids and Teens Resource Centre, Akure, Nigeria

Abstract

Background In 2016, Nigeria transitioned to ‘Test & Treat’, a policy where all people living with HIV (PLHIV) are treated with lifelong antiretroviral therapy (ART) regardless of clinical or immunological status. Hypothesis tested was antiretroviral therapy adherence effect on viral load outcome. The aim of this study is to assess the viral load suppression rates among HIV positive pregnant & breastfeeding women in Western Nigeria.

Methods This study was an observational prospective study of pregnant & breastfeeding HIV positive subjects already initiated on antiretroviral therapy for at least six months, enrolled in health facilities across supported facilities in Western Nigeria, during a 12-month observation period starting October 2016 till September 2017. Quantitative viral load analysis was done using Polymerase Chain Reaction, Roche Cobas Taqman 96 Analyzer.

Results A total of 243 subjects were recruited. The mean age of 32.58 ± 4.18 years. 69 are breastfeeding while 174 were pregnant women. 208 (85.6%) & 188 (77.4%) had viral suppression of <1000 & <50 RNA copies per ml respectively. The 35 subjects went through peer counseling by trained PLHIV and enhanced adherence counseling (EAC) for three months and viral load test repeated three further months after, which made 221 (90.9%) & 202 (83.1%) of the subjects have <1000 RNA & <50 RNA copies per ml respectively during the observation. The PLHIVs joined the institutionalized social-media driven support group & decentralized care model ensuring they achieve the third 90 at undetectable level. ART adherence has significant effect on viral load outcome (χ² = 5.86, df = 1, P = 0.001).

Conclusion ART adherence counseling is key to the achieving viral suppression and determine infection prognosis, thus, developing robust continuous quality improvement (CQI) plans to address issues across the cascade ultimately helping in the monitoring of HIV/AIDS disease progression and decrease treatment failure tendencies.

Disclosure No significant relationships.

  • prevention
  • intervention and treatment
  • pregnancy and contraception
  • Nigeria

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