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S09.3 Application of a cascade approach for guiding prevention of congenital syphilis
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  1. Patricia Garcia
  1. Cayetano Heredia University, Unit of Epidemiology, STIs and HIV, Lima, Peru

Abstract

Syphilis remains a major public health problem worldwide especially in developing countries and in the region of Latin America and the Caribbean (LAC). Congenital syphilis is caused by mother-to-child transmission of the Treponema pallidum infection during pregnancy. Transmission can occur during any trimester of pregnancy and during any stage of syphilis. Nevertheless, the risk of transmission is highest during early syphilis (primary, secondary, or early latent syphilis). Untreated syphilis in pregnancy can result in adverse pregnancy outcomes including miscarriages, stillbirth, neonatal death, as well as prematurity, low birth weight and other congenital abnormalities. Congenital syphilis is preventable. Treatment to the infected mother with a long acting injectable penicillin (benzathine penicillin G) can prevent stillbirths and fetal infection if initiated as early as possible during pregnancy or at least 30 days before delivery. Many the countries of the LAC region have committed to reduce cases of congenital syphilis to less than 0.5 cases per 1,000 live births, however many of them are still far from achieving the objective. The reduction or elimination of congenital syphilis can be performed with simple, cost-effective interventions, like screening and treating pregnant women early in antenatal care. Peru has also a commitment to eliminate congenital syphilis and introduced the use of rapid syphilis tests for screening to simplify the testing and improve coverage. However, if a woman is tested and don’t receive treatment there is a failure of the system, a broken care continuum. The concept of care cascades has been used to analyze the HIV care continuum and to evaluate other STD control activities. We decided to use Peruvian National data to create a congenital syphilis prevention cascade to visualize the current status of activities and identify opportunities for improvement.

Disclosure No significant relationships.

  • congenital syphilis
  • cascade
  • prevention
  • infants and neonates

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