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P471 Lymphogranuloma venerum in Quebec, Canada: five years of epidemiological survey, 2013–2017
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  1. Dieynaba Diallo1,
  2. Sylvie Venne2,
  3. Annie-Claude Labb3,
  4. Marc Fiset4,
  5. France Markowski4,
  6. Donald Murphy5,
  7. Jean Longtin5,
  8. Marc Dionne1,
  9. Catherine-Audrey Boutin3,
  10. Karine Blouin1,6
  1. 1Direction des risques biologiques et de la santé au travail; Institut national de santé publique du Québec
  2. 2Direction de la prévention des ITSS, Ministère de la santé et des services sociaux du Québec
  3. 3Département de microbiologie, infectiologie et immunologie, Université de Montréal; Québec, Canada
  4. 4Direction de la vigie sanitaire, Ministère de la sant et des services sociaux du Québec
  5. 5Laboratoire de santé publique du Québec, Institut national de santé publique du Québec
  6. 6Département de médecine sociale et préventive, Université de Montréal

Abstract

Background Reported cases of lymphogranuloma venerum (LGV) were unusual in Quebec before 2005, when a first epidemic occurred (25 cases in 2005, 44 cases in 2006). This was followed by a low-endemicity period between 2007 and 2012 (2 to 13 cases/year). Since 2013, the number of reported LGV cases strongly increased with a peak in 2016 (2013: 49, 2014: 61, 2015: 105, 2016: 124 and 2017: 105). We hereby report on enhanced LGV surveillance between January 1st 2013 and December 31st 2017.

Methods We used data from the notifiable diseases records, epidemiological investigation questionnaires and genotyping to describe the evolution of this resurgence. Since June 2016, all Chlamydia-positive anorectal samples are sent to the Laboratoire de santé publique du Québec for genotyping. Collected information includes demographics, risk factors (for the past year unless otherwise indicated), clinical manifestations, laboratory tests and treatments.

Results All male reported cases (442, 97% confirmed) were analyzed (399 with available questionnaire). Most cases were L2b genotype (98%) and lived in Montreal (81%). Mean age was 40 years. Almost all (97%) were men who have sex with men (MSM), 94% reported past sexually transmitted infection (STI) and 78% were HIV-infected (243/311). LGV-specific symptoms were reported by 69% of cases, 11% mentioned non LGV-specific symptoms and 21% were asymptomatic. Sex partners outside Quebec were reported by 37% of cases, 51% have had more than 10 sex partners and 58% have used recreational drug. LGV reinfection occurred among 45 persons (11%): 36 had 2 episodes, 9 had 3 episodes and 1 had 4 episodes. In 2017 (first complete year of routine genotyping on Chlamydia-positive anorectal samples), 100/1591 (6.3%) were LGV genotypes.

Conclusion The LGV epidemic is still ongoing. Cases are mostly from urban regions, are almost exclusively MSM and frequently report past STIs, a high number of sex partners and drugs use.

Disclosure No significant relationships.

  • trends
  • chlamydia

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