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P542 Prevalence of STIs among MSM initiating PrEP in west-africa (CohMSM-PrEP ANRS 12369 – expertise france)
  1. Irith De Baetselier1,
  2. Tania Crucitti2,
  3. Issifou Yaya3,
  4. Bintou Dembele4,
  5. Ephrem Mensah5,
  6. Elias Dah6,
  7. Amadou Koné7,
  8. Hortense Fayé-Ketté8,
  9. Souba Diandé9,
  10. Alain Yeo8,
  11. Anoumou Dagnra10,
  12. Christian Laurent3,
  13. Bea Vuylsteke11
  1. 1Institute of Tropical Medicine, Clinical Sciences, Antwerp, Belgium
  2. 2Institut Pasteur du Cameroun, Yaoundé, Cameroon
  3. 3IRD, INSERM, Montpellier, France
  4. 4ARCAD/SIDA, Bamako, Mali
  5. 5Espoir Vie Togo, Lomé, Togo
  6. 6Association African Solidarité, Ouagadougou, Burkina Faso
  7. 7SEREFO/UCRC, USTTB, Bamako, Mali
  8. 8Institut Pasteur Côte d’Ivoire, Abdijan, Côte d’Ivoire
  9. 9LNR-TB, Ouagadougou, Burkina Faso
  10. 10CHU-SO-LNR-TB, Lomé, Togo
  11. 11Institute of Tropical Medicine, Department of Public Health, Antwerp, Belgium

Abstract

Background Men who have sex with men (MSM) coming forward for Pre-Exposure Prophylaxis (PrEP) are at high risk for HIV and other Sexually Transmitted Infections (STIs). However, little is known about the prevalence of STIs among MSM in West-Africa. Yet, understanding the STI epidemic among MSM will improve STI management. In the framework of a PrEP demonstration study in West-Africa (CohMSM-PrEP), we tested all participants for STIs at enrollment.

Methods The study was conducted in Abidjan-Côte d’Ivoire, Bamako-Mali, Lomé-Togo and Ouagadougou-Burkina Faso. Participants (n=507) were tested for the following STIs using the GeneXpert instrument: Chlamydia trachomatis (CT)/Neisseria gonorrhoeae (NG) in Anorectum (A), Urine (U) and Pharynx (P), and Trichomonas vaginalis (TV) in urine. Mycoplasma genitalium (MG) was tested using the S-DiagMGTV multiplex assay in A-U-P samples.

Results The overall prevalence of CT was 17.9% (19.4%, 22.0% 16.4%, and 13.6% in Lomé, Abidjan, Bamako and Ouagadougou, respectively). Most CT infections were anorectal (12.3%, followed by urethral (5.7%). In Bamako, the second most infected sample type was pharyngeal (6.0%) instead of urine (5.0%). Overall prevalence of NG was 15.8% (9.7%; 25.0%; 6.0%, 22.3% in Lomé, Abidjan, Bamako and Burkina, respectively). Most NG infections were found in the anorectum (10.7%), followed by the pharynx (5.7%). In Mali, no pharyngeal NG infections were detected. MG infection was 26.0% for Lomé and 27.6% for Ouagadougou (results for other sites not yet available). The majority of MG infections were found in the anorectum (15.4%). Among all participants, only one urine sample with TV has been found in Bamako.

Conclusion We showed a very high prevalence of extra-genital STIs among PrEP users in West-Africa. We also detected infections which would not have been treated if a syndromic management approach would have been applied (87.9%). In order to limit transmission of infections we recommend to test also extra-genital sites for STIs in this population.

Disclosure No significant relationships.

  • ART
  • PrEP
  • modeling and prevalence
  • gay bisexual and other men who have sex with men

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