Gonorrhea is a major public health concern in South East Asia including Thailand. In 2016, 9434 (14.3/100,000 population) of gonorrhea cases were reported. Complications including pelvic inflammatory disease, ectopic pregnancy and infertility compound the disease burden. Antimicrobial resistance (AMR) in Neisseria gonorrhoeae (NG) has been monitored. In addition, the novel Enhanced Gonococcal Antimicrobial Surveillance Program (EGASP) was initiated in 2015. Review the approach of public health on prevention, surveillance data and responses to the treat of AMR in NG including the EGASP in Thailand. This presentation will include the burden of gonorrhea, gonococcal antimicrobial susceptibilities to the drugs currently recommended for the treatment of gonorrhea (ceftriaxone, cefixime, and azithromycin), development of prevention strategies and responses to the threat of AMR gonorrhea and challenges. Public health approach on gonorrhea prevention is crucial and the threat of AMR in NG driven the urgent need to strengthen Gonococcal Antimicrobial Surveillance Program and rapid response to treatment failure gonorrhea cases and control the spreading of AMR NG. Effective and combination prevention strategies at country and global level is needed.

Disclosure No significant relationships.