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Frequent clearance of oral human papillomavirus (HPV) infection in men who have sex with men (MSM) with and without HIV
Oral HPV infection, usually acquired through oral sex, may play a role in oropharyngeal cancer.1 This study prospectively collected 856 oral rinse-and-gargle samples from 244 MSM, including 103 (42%) with HIV who were mostly on virologically suppressive antiretroviral therapy. Over a median of 13 months, incidence of HPV DNA positivity (×1000 person-months) among MSM with HIV was 21.2 for any HPV type (vs 15.0 in MSM without HIV) and 10.7 for high-risk types (vs 6.5). Clearance rates were 82.8 (vs 92.8) and 121.1 (vs 82.7), respectively; both older age and a low nadir CD4 count predicted reduced clearance of high-risk HPV types among MSM with HIV. Thus, oral HPV infections occur among MSM but are less common and show higher spontaneous clearance rates than previously reported for anal infections.2 HPV vaccination is important for this population.
Giuliani M, Rollo F, Vescio MF, et al. Oral human papillomavirus infection in HIV-infected and HIV-uninfected MSM: the OHMAR prospective cohort study. Sex Transm Infect 2020;96:528-536. doi: 10.1136/sextrans-2019-054301.
Are Emergency Departments (EDs) cost-effective venues for STI screening in young adults?
The highest rates of STI diagnoses are observed in young adults,3 4 and tailored screening strategies are needed. ED-based screening can be feasible and acceptable for young adults.5 This study used literature-based estimates to model three testing strategies for …
Handling editor Anna Maria Geretti
Contributors All authors contributed equally to the manuscript.
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.