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Putting the ‘Eye’ in Spirochaetes
  1. Cristina Corsini Campioli1,
  2. John Raymond Go1,
  3. Madiha Fida1,
  4. Douglas Challener1,
  5. Muhammad Rizwan Sohail2,
  6. Omar Abu Saleh1,
  7. Sarwat Khalil3
  1. 1 Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA
  2. 2 Infectious Diseases, Baylor College of Medicine, Houston, Texas, USA
  3. 3 Infectious Diseases, University of Minnesota, Minneapolis, Minnesota, USA
  1. Correspondence to Dr Cristina Corsini Campioli, Infectious Diseases, Mayo Clinic, Rochester, MN 55904, USA; corsinicampioli.cristina{at}

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In 2018, the Centers for Disease Control and Prevention reported an alarming increase in syphilis infection rates, and the numbers have continued to rise since, with rates highest in men who have sex with men (MSM). Ocular syphilis, often seen in association with neurosyphilis, is a rare manifestation of Treponema pallidum infection, and reported rates are also increasing.1 Therefore, we aimed to describe clinical and laboratory characteristics of patients with ocular syphilis, and retrospectively reviewed all adult patients diagnosed …

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  • Handling editor Anna Maria Geretti

  • Contributors CCC designed the data collection tools, monitored the data collection, wrote the statistical analysis plan, cleaned and analysed the data, and drafted and revised the paper. JRG and OAS analysed the data, and drafted and revised the paper. DC, MF and MRS revised the draft paper. SK monitored the data collection and revised the draft paper.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.