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Correspondence
Prolonged neuropsychiatric symptoms may delay the diagnosis of parkinsonism secondary to neurosyphilis
  1. Kundian Guo1,2,
  2. Chunxia Jiang3,
  3. Zhen Hong1,2,
  4. Zaiquan Dong4
  1. 1 Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China
  2. 2 Institute of Brain science and Brain-inspired technology of West China Hospital, Sichuan University, Chengdu, Sichuan, China
  3. 3 Department of Ophthalmology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China
  4. 4 Mental Health Center of West China Hospital, Sichuan University, Chengdu, Sichuan, China
  1. Correspondence to Dr Zaiquan Dong, Mental Health Center of West China Hospital, Sichuan University, Chengdu 610041, Sichuan, People's Republic of China; quanzaidong{at}126.com; Dr Zhen Hong, Department of neurology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, People's Republic of China; hongzhengoog{at}aliyun.com

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Dear Editor,

A 49-year-old man without a family history of neuropsychiatric diseases was admitted to the Department of Psychiatry 1 year after first developing depressed mood, feelings of despair, insomnia, fatigue and poor concentration, without other neuropsychiatric signs or symptoms, which had led to a diagnosis of depression. Despite receiving antidepressants for 3 months, the symptoms had not improved. On admission, neurological examination revealed decreased cognition, mask-like face, positive glabellar reflex, tongue tremor, four-limb cogwheel rigidity, wide-base short steps …

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Footnotes

  • Handling editor Anna Maria Geretti

  • KG and CJ contributed equally.

  • Contributors KG and CJ collected the data and drafted the manuscript. ZH revised the manuscript. ZD conceptualised and revised the manuscript.

  • Funding This work was supported by the Key R&D Projects of Science and Technology, Department of Sichuan Province (grant no. 2019YFS0217).

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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