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A case of chronic bacterial prostatitis due to Mycoplasma genitalium
  1. Roberto Rossotti,
  2. Giovanna Travi,
  3. Nicholas Brian Bana,
  4. Carloandrea Orcese,
  5. Massimo Puoti
  1. Department of Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda, School of Medicine and Surgery, Milano, Italy
  1. Correspondence to Dr Roberto Rossotti, Department of Infectious Diseases, ASST Grande Ospedale Metropolitano Niguarda, Milano 20162, Italy; roberto.rossotti{at}


Mycoplasma genitalium (MG) is a common cause of non-gonococcal urethritis, but a role in acute or chronic prostatitis has not been described. We describe the case of a 42-year-old man with recurrent urinary tract infections since 2018 who developed chronic prostatitis despite several and prolonged antibiotic courses. Multiparametric prostatic magnetic resonance showed peripheral inflammatory alterations. A 4-glass Meares-Stamey test detected MG in the third voided bladder (VB3) sample. Moxifloxacin 400 mg daily for 28 days resulted in sustained clinical and microbiological cure.

  • Mycoplasma genitalium

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  • Handling editor Anna Maria Geretti

  • Contributors GT, NBB and CO were the treating physicians. MP made intellectual contributions to the concept of the study, supervised the study, validated and edited the first draft.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

  • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.